Pulling SEC filings + quote and writing the call…
Pulling SEC filings + quote and writing the call…

Krystal Biotech, Inc.
Next earnings Aug 3, 2026 (before open) · consensus $1.79 EPS, $128M rev
Last earnings +4.1% on 2026-02-17
Profitable rare-disease gene-therapy story: VYJUVEK at 94% gross margin, global launches ramping, debt-free, with real pipeline optionality.
Sources: SEC EDGAR (CIK 0001711279, latest 10-Q filed 2026-05-04) · EODHD · analysis by claude-code · as of 6/21/2026, 8:49:35 PM.
Research and education only — not financial advice. Calls are generated from SEC filings and a delayed/third-party price feed, may be wrong or out of date, and are not a recommendation to buy or sell any security. Do your own research.
The fundamentals carry the rating, but the price is rich (~26% above our fair-value estimate) — a quality-at-a-price call. The case rests on the business, not the entry; patient buyers may wait for a pullback.
Krystal Biotech has made the rare leap from clinical-stage biotech to a genuinely profitable commercial company. Its HSV-1-based gene-therapy platform produced VYJUVEK, an approved, redosable topical treatment for dystrophic epidermolysis bullosa (DEB). Revenue has scaled fast — from $50.7M in FY2023 to $291M in FY2024 to $389M in FY2025 (+33.9%) — and the economics are extraordinary for a drug: 94% product gross margin, a 41.5% operating margin and a 52.6% net margin. Net income more than doubled to $205M (+129.7%) and diluted EPS rose to $6.84.
The risks, catalysts, 12-month price target and the cited SEC figures behind this rating — with Pro.
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| Line item | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|
| Revenue | $0.00 | $0.00 | $50.7M | $291M | $389M |
| Gross profit | — | — | — | — | — |
| Operating income | -$68.3M | -$145M | -$110M | $65.7M | $161M |
| Net income | -$69.6M | -$140M | $10.9M | $89.2M | $205M |
| Diluted EPS | -$3.13 | -$5.49 | $0.39 | $3.00 | $6.84 |
| Net margin | — | — | 21.6% | 30.7% | 52.6% |
Annual figures from SEC 10-K XBRL filings. Open the filing links below for full statement detail.
Computed from SEC XBRL annual figures + the current quote. EV and ROIC use long-term + current debt where filed; estimates, not investment advice.
Disclosed under the STOCK Act
Self-reported periodic transaction reports (STOCK Act). Amounts are disclosed ranges; a trade may be a spouse's. Disclosures lag the trade by up to ~45 days. Source: House Clerk + Senate eFD.
1482 tracked peers · median
Dates from 8-K (Item 2.02); beat/miss = reported EPS vs consensus (Finnhub, recent quarters); move = prior close → close on/after.
Last 90 days: 0 open-market buys · 23 sales
| 2026-06-04 | Krishnan Suma President, R&D | Sell | 320.00 @ $300.75 | $96.2K |
| 2026-06-04 | Krishnan Suma President, R&D | Sell | 593.00 @ $302.25 | $179K |
| 2026-06-04 | Krishnan Suma President, R&D | Sell | 247.00 @ $303.17 | $74.9K |
| 2026-06-04 | Krishnan Suma President, R&D | Sell | 400.00 @ $304.89 | $122K |
| 2026-06-04 | Krishnan Suma President, R&D | Sell | 480.00 @ $305.87 | $147K |
| 2026-06-04 | Krishnan Suma President, R&D | Sell | 1.35K @ $307.09 | $414K |
| 2026-06-04 | Krishnan Suma President, R&D | Sell | 12.7K @ $307.81 | $3.92M |
| 2026-06-04 | Krishnan Suma President, R&D | Sell | 3.80K @ $308.89 | $1.17M |
| 2026-06-04 | Krishnan Suma President, R&D | Sell | 2.80K @ $309.95 | $868K |
| 2026-06-04 | Krishnan Suma President, R&D | Sell | 2.04K @ $310.94 | $634K |
| 2026-06-04 | Krishnan Suma President, R&D | Sell | 240.00 @ $311.65 | $74.8K |
| 2026-06-04 | Krishnan Krish S President and CEO | Sell | 320.00 @ $300.75 | $96.2K |
Recent news tone vs the market's typical (which skews positive). A soft signal, not a recommendation.