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Research & education only — not financial advice. EDGAR is not a registered investment adviser; calls are impersonal, generated from SEC filings and a delayed/third-party price feed, and may be wrong or out of date. The operator and an affiliated trading operation may hold or trade the securities EDGAR rates — see Disclosures. Do your own research.

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Home›Stocks›ARWR

ARWR

ARROWHEAD PHARMACEUTICALS, INC.

Next earnings Aug 5, 2026 · consensus $-1.33 EPS, $56.0M rev

Last earnings -1.5% on 2026-05-07

Hold
$78.89
▼ -0.48%
$78.89▲ +408.64%
over 1Y
L $14.71EODHDH $82.00
Earnings Dividend Split Congress buy Congress sellGrouped by date · hover a pin to expand
Today-0.5%
1W-3.8%
1M-0.1%
3M+36.5%
YTD+16.4%
1Y+408.6%
OverviewFinancialsValuationQualityTimelineFilings
Rating
Hold
Quality
C
Valuation
Fair value
Filings
Watch
Hold
Conviction
Horizon
Long (>12mo)
Street · 20 analysts
Buy

RNAi biotech de-risked by big-pharma deals — now cash-flow positive, but value still rides on unproven clinical pipelines.

Revenue $829M · FY2025

Arrowhead Pharmaceuticals has transformed its financial profile through major partnerships. FY2025 revenue jumped to $829M (from just $3.55M in FY2024), driven by upfront and milestone payments, and the company swung to positive operating income of $98.3M and operating cash flow of $180M — a sharp reversal from the -$463M operating cash burn in FY2024. Net income was essentially breakeven at -$1.63M. The MD&A details the catalysts: a Sarepta collaboration delivering a $500M upfront plus $100M and $200M DM1 milestones, and an October 2025 Novartis deal with a $200M upfront. These validate Arrowhead's RNAi platform with deep-pocketed partners.

Financials · annual, by fiscal year

Line itemFY21FY22FY23FY24FY25
Revenue$138M$243M$241M$3.55M$829M
Gross profit—————
Operating income-$149M-$179M-$205M-$601M$98.3M
Net income-$141M-$176M-$205M-$599M-$1.63M
Diluted EPS-$1.36-$1.67-$1.92-$5.00-$0.01
Net margin-101.9%-72.4%-85.3%-16882.4%-0.2%

Annual figures from SEC 10-K XBRL filings. Open the filing links below for full statement detail.

Key statistics

Valuation

Enterprise value$10.5B
EV / EBITDA87.0
EV / Sales12.6
EV / FCF66.8
P / FCF68.3
PEG (trailing)—
Earnings yield-0.0%
FCF yield1.5%

Quality & risk

ROIC (est.)16.7%
Free cash flow$157M
Total debt—
Net cash$227M
Piotroski F-Score4/7

Capital returns

Buyback yield—
Dividend yield (est.)—
Shareholder yield—
Shares Δ YoY+9.1%

Computed from SEC XBRL annual figures + the current quote. EV and ROIC use long-term + current debt where filed; estimates, not investment advice.

Disclosure timeline

SEC · 8-Ks + reports
Some governance/structural items recently, but no outright red flags.
  1. 8-K Officer / director change2026-06-16
  2. 8-K Earnings results2026-05-07
  3. 10-Q Quarterly report2026-05-07
  4. 8-K Shareholder vote2026-03-20
  5. 8-K Earnings results2026-02-05
  6. 10-Q Quarterly report2026-02-05
  7. DEF 14A Proxy statement2026-01-27
  8. 8-K Material agreement2026-01-12
  9. 8-K Material agreement2026-01-09

Recent filings

all on EDGAR ↗
4Period ending 2026-06-152026-06-17open ↗3Period ending 2026-06-152026-06-17open ↗8-KPeriod ending 2026-06-122026-06-16open ↗144/AFiling2026-05-19open ↗144/AFiling2026-05-19open ↗144/AFiling2026-05-19open ↗4Period ending 2026-05-122026-05-14open ↗144Filing2026-05-12open ↗S-8Filing2026-05-07open ↗10-QPeriod ending 2026-03-312026-05-07open ↗8-KPeriod ending 2026-05-072026-05-07open ↗SCHEDULE 13GFiling2026-05-06open ↗

Quality score

C
ValueGrowthProfitHealthMom.
ValueF
GrowthA+
ProfitabilityF
Financial healthC
Momentum—
  • ✓Revenue growing year-over-year
  • ✗Profitable (positive net income)
  • ✗Net margin above 10%
  • ✗Return on equity above 15%
Revenue
$829M
+23258.2% YoY
Net margin
-0.2%
ROE
-0.3%
P/E
—

SEC fundamentals · FY 2025

'21'22'23'24'25

■ revenue · ■ net income, by fiscal year

Revenue$829M+23258.2%
Net income-$1.63M+99.7%
Operating income$98.3M+116.4%
Diluted EPS-$0.01+99.8%
Cash & equivalents$227M+120.6%
Total assets$1.39B+21.5%
Stockholders' equity$466M+151.3%
Op.: 11.9%

Frequently asked

Is ARROWHEAD PHARMACEUTICALS, INC. (ARWR) a buy?
ARWR currently carries a Hold rating with 3/5 conviction, derived from its latest SEC filings. RNAi biotech de-risked by big-pharma deals — now cash-flow positive, but value still rides on unproven clinical pipelines.
What is ARROWHEAD PHARMACEUTICALS, INC.'s quality score?
ARWR scores 55.11764705882352/100 (grade C) on a SEC-grounded quality model spanning value, growth, profitability, financial health and momentum.

Sources: SEC EDGAR (CIK 0000879407, latest 10-Q filed 2026-05-07) · EODHD · analysis by claude-code · as of 6/21/2026, 8:48:14 PM.

Research and education only — not financial advice. EDGAR is not a registered investment adviser or broker-dealer and gives no personalized advice. Every call is impersonal — identical for all users, generated on a schedule from SEC filings plus a delayed/third-party price feed — may be wrong or out of date, and is not a recommendation to buy or sell any security. The operator and an affiliated trading operation may hold or trade the securities EDGAR rates; see Disclosures. Past performance does not guarantee future results. Do your own research.

Insider activity

Form 4 · SEC

Last 90 days: 0 open-market buys · 5 sales

2026-06-15
Cohen Matthew Gregory
Director
Award11.9K
2026-05-12
Lu Hongbo
Director
Sell2.97K @ $76.88$228K
2026-04-23
Hamilton James C
Chief Medical Officer
Sell10.0K @ $75.00$750K
2026-04-22
Apel Daniel Joseph
Chief Financial Officer
Sell3.21K @ $70.11$225K
2026-04-22
Apel Daniel Joseph
Chief Financial Officer
Sell1.16K @ $70.45$81.5K
2026-04-22
Apel Daniel Joseph
Chief Financial Officer
Sell8.73K @ $71.92$628K
2026-03-05
Hamilton James C
Chief Medical Officer
Sell10.0K @ $64.19$642K
2026-01-06
Hamilton James C
Chief Medical Officer
Award75.0K
2026-01-06
Apel Daniel Joseph
Chief Financial Officer
Award75.0K
2026-01-06
O'Brien Patrick
COO
Gift540.00
2026-01-06
O'Brien Patrick
COO
Gift540.00
2026-01-06
O'Brien Patrick
COO
Gift540.00

Earnings history

beat/miss · move
2026-05-07Beat +23.2% est▼ -1.50%8-K ↗
2026-02-05Miss -14.8% est▼ -5.02%8-K ↗
2025-11-25Beat +26.7% est▲ +5.72%8-K ↗
2025-08-07Miss -20.5% est▼ -1.53%8-K ↗
2025-05-12—▲ +7.21%8-K ↗
2025-02-10—▼ -1.58%8-K ↗

Dates from 8-K (Item 2.02); beat/miss = reported EPS vs consensus (Finnhub, recent quarters); move = prior close → close on/after.

Congressional trades

all activity →

Disclosed under the STOCK Act

2023-02-24Daniel GoldmanSell$1.00K–$15.0KPTR ↗

Self-reported periodic transaction reports (STOCK Act). Amounts are disclosed ranges; a trade may be a spouse's. Disclosures lag the trade by up to ~45 days. Source: House Clerk + Senate eFD.

Recent news

market news →
3 Under-the-Radar Biotech Takeover Targets for the Next Pharma Buying SpreeBullish
finance.yahoo.com· 2026-06-25
Arrowhead Pharmaceuticals Receives Marketing Authorization in the European Union for REDEMPLO® (plozasiran) to Reduce Triglycerides in Adults with Familial Chylomicronemia Syndrome (FCS)Bullish
finance.yahoo.com· 2026-06-22
Arrowhead Pharmaceuticals to Host a Webinar on its Cardiometabolic Pipeline as Part I of the 2026 Summer Series of R&D WebinarsBullish
finance.yahoo.com· 2026-06-18
Arrowhead Pharmaceuticals to Participate in Upcoming June 2026 EventsBullish
finance.yahoo.com· 2026-06-02
Arrowhead Pharmaceuticals Presents New Clinical Data on RNAi-based Obesity and MASH Candidate ARO-INHBE at EASL 2026Bullish
finance.yahoo.com· 2026-05-27
Arrowhead Data On Plozasiran Expands Cardiometabolic Opportunity And Investor FocusBullish
finance.yahoo.com· 2026-05-26

Vs tracked universe

compare →

1042 tracked peers · median

EDGAR Score55 vs 67
Revenue growth23258.2% vs 7.1%
Net margin-0.2% vs 10.5%
Return on equity-0.3% vs 12.4%
P/E— vs 25.5

News sentiment

EODHD · 15d
Bullish
+0.17
vs typical · 21 articles

Recent news tone vs the market's typical (which skews positive). A soft signal, not a recommendation.