Pulling SEC filings + quote and writing the call…

ARROWHEAD PHARMACEUTICALS, INC.
Next earnings Aug 5, 2026 · consensus $-1.33 EPS, $56.0M rev
Last earnings -1.5% on 2026-05-07
RNAi biotech de-risked by big-pharma deals — now cash-flow positive, but value still rides on unproven clinical pipelines.
Revenue $829M · FY2025
Arrowhead Pharmaceuticals has transformed its financial profile through major partnerships. FY2025 revenue jumped to $829M (from just $3.55M in FY2024), driven by upfront and milestone payments, and the company swung to positive operating income of $98.3M and operating cash flow of $180M — a sharp reversal from the -$463M operating cash burn in FY2024. Net income was essentially breakeven at -$1.63M. The MD&A details the catalysts: a Sarepta collaboration delivering a $500M upfront plus $100M and $200M DM1 milestones, and an October 2025 Novartis deal with a $200M upfront. These validate Arrowhead's RNAi platform with deep-pocketed partners.
| Line item | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|
| Revenue | $138M | $243M | $241M | $3.55M | $829M |
| Gross profit | — | — | — | — | — |
| Operating income | -$149M | -$179M | -$205M | -$601M | $98.3M |
| Net income | -$141M | -$176M | -$205M | -$599M | -$1.63M |
| Diluted EPS | -$1.36 | -$1.67 | -$1.92 | -$5.00 | -$0.01 |
| Net margin | -101.9% | -72.4% | -85.3% | -16882.4% | -0.2% |
Annual figures from SEC 10-K XBRL filings. Open the filing links below for full statement detail.
Computed from SEC XBRL annual figures + the current quote. EV and ROIC use long-term + current debt where filed; estimates, not investment advice.
Sources: SEC EDGAR (CIK 0000879407, latest 10-Q filed 2026-05-07) · EODHD · analysis by claude-code · as of 6/21/2026, 8:48:14 PM.
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Last 90 days: 0 open-market buys · 5 sales
| 2026-06-15 | Cohen Matthew Gregory Director | Award | 11.9K | |
| 2026-05-12 | Lu Hongbo Director | Sell | 2.97K @ $76.88 | $228K |
| 2026-04-23 | Hamilton James C Chief Medical Officer | Sell | 10.0K @ $75.00 | $750K |
| 2026-04-22 | Apel Daniel Joseph Chief Financial Officer | Sell | 3.21K @ $70.11 | $225K |
| 2026-04-22 | Apel Daniel Joseph Chief Financial Officer | Sell | 1.16K @ $70.45 | $81.5K |
| 2026-04-22 | Apel Daniel Joseph Chief Financial Officer | Sell | 8.73K @ $71.92 | $628K |
| 2026-03-05 | Hamilton James C Chief Medical Officer | Sell | 10.0K @ $64.19 | $642K |
| 2026-01-06 | Hamilton James C Chief Medical Officer | Award | 75.0K | |
| 2026-01-06 | Apel Daniel Joseph Chief Financial Officer | Award | 75.0K | |
| 2026-01-06 | O'Brien Patrick COO | Gift | 540.00 | |
| 2026-01-06 | O'Brien Patrick COO | Gift | 540.00 | |
| 2026-01-06 | O'Brien Patrick COO | Gift | 540.00 |
Dates from 8-K (Item 2.02); beat/miss = reported EPS vs consensus (Finnhub, recent quarters); move = prior close → close on/after.
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1042 tracked peers · median
Recent news tone vs the market's typical (which skews positive). A soft signal, not a recommendation.