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Research & education only — not financial advice. EDGAR is not a registered investment adviser; calls are impersonal, generated from SEC filings and a delayed/third-party price feed, and may be wrong or out of date. The operator and an affiliated trading operation may hold or trade the securities EDGAR rates — see Disclosures. Do your own research.

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Home›Stocks›CBIO

CBIO

CRESCENT BIOPHARMA, INC.

Last earnings -12.6% on 2026-04-29

Sell
$18.56
▲ +9.24%
$18.56▲ +21.31%
over 1Y
L $8.94EODHDH $26.98
Earnings Dividend Split Congress buy Congress sellGrouped by date · hover a pin to expand
Today+9.2%
1W+5.6%
1M-10.7%
3M+22.4%
YTD+67.5%
1Y+21.3%
OverviewFinancialsValuationQualityTimelineFilings
Rating
Sell
Quality
F
Valuation
Fair value
Filings
Flagged
Sell
Conviction
Horizon
Medium (3–12mo)
Street · 15 analysts
Strong Buy

Conservative balance sheet (liabilities/equity 0.18x); but unprofitable (net margin -1419.6%).

Revenue (FY2025) $10.8M · FY2025

CRESCENT BIOPHARMA, INC. shows $10.8M in FY2025 revenue, a -1419.6% net margin, and -75.8% ROE.

Financials · annual, by fiscal year

Line itemFY21FY22FY23FY24FY25
Revenue————$10.8M
Gross profit—————
Operating income-$63.4M-$47.4M-$39.3M-$40.0M-$153M
Net income-$63.4M-$46.7M-$36.9M-$37.9M-$154M
Diluted EPS-$1.23-$0.89-$0.58-$0.59—
Net margin————-1419.6%

Annual figures from SEC 10-K XBRL filings. Open the filing links below for full statement detail.

Key statistics

Valuation

Enterprise value$298M
EV / EBITDA—
EV / Sales27.5
EV / FCF—
P / FCF—
PEG (trailing)—
Earnings yield-30.1%
FCF yield-14.2%

Quality & risk

ROIC (est.)-59.4%
Free cash flow-$72.5M
Total debt—
Net cash$213M
Altman Z-Score6.18 safe
Piotroski F-Score4/6

Capital returns

Buyback yield—
Dividend yield (est.)—
Shareholder yield—
Shares Δ YoY-57.3%

Computed from SEC XBRL annual figures + the current quote. EV and ROIC use long-term + current debt where filed; estimates, not investment advice.

Disclosure timeline

SEC · 8-Ks + reports
Red flag in recent filings — restated periodic report (2026-06-22). Worth a closer look.
  1. 10-Q/A Restated periodic report2026-06-22
  2. 8-K Shareholder vote2026-06-03
  3. 8-K Earnings results2026-04-29
  4. 10-Q Quarterly report2026-04-29
  5. DEF 14A Proxy statement2026-04-21
  6. 8-K Earnings results2026-02-26
  7. 10-K Annual report2026-02-26
  8. S-1 Securities registration2026-01-07
  9. 8-K Material agreement2025-12-04

Recent filings

all on EDGAR ↗
4Period ending 2026-06-222026-06-23open ↗4Period ending 2026-06-222026-06-23open ↗4Period ending 2026-06-222026-06-23open ↗4Period ending 2026-06-222026-06-23open ↗4Period ending 2026-06-222026-06-23open ↗4Period ending 2026-06-222026-06-23open ↗4Period ending 2026-06-222026-06-23open ↗424B3Filing2026-06-22open ↗10-Q/APeriod ending 2026-03-312026-06-22open ↗4Period ending 2026-06-022026-06-03open ↗4Period ending 2026-06-022026-06-03open ↗4Period ending 2026-06-022026-06-03open ↗

Quality score

F
ValueGrowthProfitHealthMom.
ValueF
GrowthF
ProfitabilityF
Financial healthB-
Momentum—
  • ✗Profitable (positive net income)
  • ✗Net margin above 10%
  • ✗Return on equity above 15%
  • ✓Liabilities below 2× equity
Revenue
$10.8M
Net margin
-1419.6%
ROE
-75.8%
P/E
—

SEC fundamentals · FY 2025

'21'22'23'24'25

■ revenue · ■ net income, by fiscal year

Revenue$10.8M
Net income-$154M-306.4%
Operating income-$153M-281.2%
Diluted EPS-$0.59-1.7%
Cash & equivalents$213M+513.2%
Total assets$240M+574.7%
Total liabilities$37.3M-20.8%
Stockholders' equity$203M
Op.: -1407.5%L/E: 0.18x

Frequently asked

Is CRESCENT BIOPHARMA, INC. (CBIO) a buy?
CBIO currently carries a Sell rating with 3/5 conviction, derived from its latest SEC filings. Conservative balance sheet (liabilities/equity 0.18x); but unprofitable (net margin -1419.6%).
What is CRESCENT BIOPHARMA, INC.'s quality score?
CBIO scores 31/100 (grade F) on a SEC-grounded quality model spanning value, growth, profitability, financial health and momentum.

Sources: SEC EDGAR (CIK 0001253689, latest 10-Q filed 2026-04-29) · EODHD · as of 6/26/2026, 7:28:29 PM.

Research and education only — not financial advice. EDGAR is not a registered investment adviser or broker-dealer and gives no personalized advice. Every call is impersonal — identical for all users, generated on a schedule from SEC filings plus a delayed/third-party price feed — may be wrong or out of date, and is not a recommendation to buy or sell any security. The operator and an affiliated trading operation may hold or trade the securities EDGAR rates; see Disclosures. Past performance does not guarantee future results. Do your own research.

Insider activity

Form 4 · SEC

Last 90 days: 0 open-market buys · 7 sales

2026-06-22
Lynch Ryan
See Remarks
Sell465.00 @ $17.99$8.37K
2026-06-22
Pinkas Jan
Chief Scientific Officer
Sell1.29K @ $17.99$23.2K
2026-06-22
Scalzo Richard William
Chief Financial Officer
Sell1.11K @ $17.99$20.0K
2026-06-22
Bispham Barbara Harlin
See Remarks
Sell1.22K @ $17.99$21.9K
2026-06-22
Im Ellie Eunkyung
Chief Medical Officer
Sell1.22K @ $17.99$21.9K
2026-06-22
McNeill Jonathan
President and COO
Sell20.5K @ $17.99$370K
2026-06-22
Brumm Joshua T
Chief Executive Officer
Sell42.3K @ $17.99$761K

Dividends

Irregular
Yield (TTM)
—
Annual / share
—
Last ex-date
2023-01-13
Last amount
$24.00
ex 2023-01-13$24.00
ex 2022-09-21$143.00

Source: EODHD. Yield = trailing-12-month dividends ÷ price.

Earnings history

beat/miss · move
2026-04-29Beat +27.5% est▼ -12.60%8-K ↗
2026-02-26Beat +79.0% est▼ -1.16%8-K ↗
2025-11-06Beat +37.2% est▲ +5.39%8-K ↗
2025-07-31Miss -174.2% est▼ -1.43%8-K ↗
2025-06-18—▲ +10.17%8-K ↗
2024-05-06—▼ -82.51%8-K ↗

Dates from 8-K (Item 2.02); beat/miss = reported EPS vs consensus (Finnhub, recent quarters); move = prior close → close on/after.

Recent news

market news →
Crescent Biopharma Announces Grants of Inducement AwardsBullish
globenewswire.com· 2026-06-26
Crescent Biopharma to Present at June Investor ConferencesBullish
globenewswire.com· 2026-06-02
Crescent Biopharma Announces Grants of Inducement AwardsBullish
globenewswire.com· 2026-05-29
Crescent Biopharma Announces Trial in Progress Presentation for ASCEND Study of CR-001, a PD-1 x VEGF Bispecific Antibody, at Upcoming American Society of Clinical Oncology (ASCO) 2026 Annual MeetingBullish
globenewswire.com· 2026-05-21
Crescent Biopharma to Present at May Investor ConferencesBullish
globenewswire.com· 2026-05-06
Crescent Biopharma Announces Grants of Inducement AwardsBullish
globenewswire.com· 2026-04-24

Vs tracked universe

compare →

1044 tracked peers · median

EDGAR Score31 vs 67
Revenue growth— vs 7.1%
Net margin-1419.6% vs 10.5%
Return on equity-75.8% vs 12.3%
P/E— vs 25.5

News sentiment

EODHD · 5d
Bearish
-0.04
vs typical · 5 articles
↑ improving

Recent news tone vs the market's typical (which skews positive). A soft signal, not a recommendation.