Pulling SEC filings + quote and writing the call…

Definium Therapeutics, Inc.
Next earnings Jul 29, 2026 · consensus $-0.56 EPS
Last earnings -0.9% on 2026-05-07
Pre-revenue psychedelic biotech burning $132M/yr with binary Phase 3 readouts in mid-to-late 2026 — coin-flip, not an investment.
Definium is a late-stage clinical biopharma with zero revenue across all five reported fiscal years and an accelerating cash burn — FY2025 net loss widened 69.1% to -$184M and operating cash outflow worsened 66.3% to -$132M, driven by an 80.2% jump in R&D to $118M as the company funded three concurrent Phase 3 trials (Voyage, Panorama, Emerge) for DT120 ODT, its lysergide-derived candidate for GAD and MDD. Accumulated deficit has ballooned to -$583M and share count grew 32.3% YoY to 99.7M, confirming the company funds itself by serially diluting shareholders.
| Line item | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|
| Revenue | — | — | — | — | — |
| Gross profit | — | — | — | — | — |
| Operating income | -$93.9M | -$66.3M | -$93.9M | -$104M | -$166M |
| Net income | -$93.0M | -$56.8M | -$95.7M | -$109M | -$184M |
| Diluted EPS | -$3.40 | -$1.84 | -$2.44 | -$1.54 | -$2.06 |
| Net margin | — | — | — | — | — |
Annual figures from SEC 10-K XBRL filings. Open the filing links below for full statement detail.
Computed from SEC XBRL annual figures + the current quote. EV and ROIC use long-term + current debt where filed; estimates, not investment advice.
Material agreement signed (Item 1.01) plus other event disclosure — likely licensing/financing deal.
Reg FD/other-event update; likely pipeline or trial-progress commentary ahead of readouts.
Annual meeting results: director slate elected, exec comp/officer changes ratified.
Other event disclosure — likely conference or pipeline update around Emerge MDD readout.
Other event disclosure following Q1 print; likely investor update or trial timing note.
Q1 2026: opex steps up as Voyage/Panorama/Emerge enroll; cash sufficient into key readouts.
Q1 2026: opex steps up as Voyage/Panorama/Emerge enroll; cash sufficient into key readouts.
Proxy filed for 2026 annual meeting — routine director/comp/auditor votes.
FY25: net loss widened to -$184M, R&D +80% on Phase 3 ramp; cash $258M, debt up.
Sources: SEC EDGAR (CIK 0001813814, latest 10-Q filed 2026-05-07) · EODHD · analysis by claude-code · as of 6/25/2026, 12:46:16 PM.
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Last 90 days: 0 open-market buys · 5 sales
| 2026-06-25 | Sullivan Mark Chief Legal Officer | Sell | 13.0K @ $45.03 | $586K |
| 2026-06-25 | Roberts Brandi Chief Financial Officer | Sell | 3.01K @ $45.03 | $136K |
| 2026-06-25 | Barrow Robert Chief Executive Officer | Sell | 29.2K @ $45.03 | $1.32M |
| 2026-06-25 | Karlin Daniel Chief Medical Officer | Sell | 10.0K @ $45.03 | $452K |
| 2026-06-25 | Wiley Matthew T. Chief Commercial Officer | Sell | 2.87K @ $45.03 | $129K |
| 2026-06-22 | Wiley Matthew T. Chief Commercial Officer | Award | 62.5K | |
| 2026-06-22 | Barrow Robert Chief Executive Officer | Award | 375K | |
| 2026-06-22 | Roberts Brandi Chief Financial Officer | Award | 62.5K |
Dates from 8-K (Item 2.02); beat/miss = reported EPS vs consensus (Finnhub, recent quarters); move = prior close → close on/after.
1043 tracked peers · median
Recent news tone vs the market's typical (which skews positive). A soft signal, not a recommendation.