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Research & education only — not financial advice. EDGAR is not a registered investment adviser; calls are impersonal, generated from SEC filings and a delayed/third-party price feed, and may be wrong or out of date. The operator and an affiliated trading operation may hold or trade the securities EDGAR rates — see Disclosures. Do your own research.

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Home›Stocks›DFTX

DFTX

Definium Therapeutics, Inc.

Next earnings Jul 29, 2026 · consensus $-0.56 EPS

Last earnings -0.9% on 2026-05-07

Avoid
$44.95
▲ +0.36%
$44.95▲ +537.59%
over 1Y
L $6.49EODHDH $44.95
Earnings Dividend Split Congress buy Congress sellGrouped by date · hover a pin to expand
Today+0.4%
1W+22.6%
1M+91.1%
3M+151.4%
YTD+229.5%
1Y+537.6%
OverviewFinancialsValuationQualityTimelineFilings
Rating
Avoid
Quality
F
Valuation
Fair value
Filings
Watch
Avoid
Conviction
Horizon
Short (<3mo)
Street · 22 analysts
Strong Buy

Pre-revenue psychedelic biotech burning $132M/yr with binary Phase 3 readouts in mid-to-late 2026 — coin-flip, not an investment.

Definium is a late-stage clinical biopharma with zero revenue across all five reported fiscal years and an accelerating cash burn — FY2025 net loss widened 69.1% to -$184M and operating cash outflow worsened 66.3% to -$132M, driven by an 80.2% jump in R&D to $118M as the company funded three concurrent Phase 3 trials (Voyage, Panorama, Emerge) for DT120 ODT, its lysergide-derived candidate for GAD and MDD. Accumulated deficit has ballooned to -$583M and share count grew 32.3% YoY to 99.7M, confirming the company funds itself by serially diluting shareholders.

Financials · annual, by fiscal year

Line itemFY21FY22FY23FY24FY25
Revenue—————
Gross profit—————
Operating income-$93.9M-$66.3M-$93.9M-$104M-$166M
Net income-$93.0M-$56.8M-$95.7M-$109M-$184M
Diluted EPS-$3.40-$1.84-$2.44-$1.54-$2.06
Net margin—————

Annual figures from SEC 10-K XBRL filings. Open the filing links below for full statement detail.

Key statistics

Valuation

Enterprise value$4.26B
EV / EBITDA—
EV / Sales—
EV / FCF—
P / FCF—
PEG (trailing)—
Earnings yield-4.1%
FCF yield—

Quality & risk

ROIC (est.)-35.2%
Free cash flow—
Total debt$40.6M
Net cash$217M
Piotroski F-Score1/7

Capital returns

Buyback yield—
Dividend yield (est.)—
Shareholder yield—
Shares Δ YoY+32.3%

Computed from SEC XBRL annual figures + the current quote. EV and ROIC use long-term + current debt where filed; estimates, not investment advice.

Disclosure timeline

SEC · 8-Ks + reports
Some governance/structural items recently, but no outright red flags.
  1. 8-K Material agreement2026-06-24

    Material agreement signed (Item 1.01) plus other event disclosure — likely licensing/financing deal.

  2. 8-K Reg FD disclosure2026-06-22

    Reg FD/other-event update; likely pipeline or trial-progress commentary ahead of readouts.

  3. 8-K Officer / director change2026-06-12

    Annual meeting results: director slate elected, exec comp/officer changes ratified.

  4. 8-K Other event2026-05-19

    Other event disclosure — likely conference or pipeline update around Emerge MDD readout.

  5. 8-K Other event2026-05-12

    Other event disclosure following Q1 print; likely investor update or trial timing note.

  6. 8-K Earnings results2026-05-07

    Q1 2026: opex steps up as Voyage/Panorama/Emerge enroll; cash sufficient into key readouts.

  7. 10-Q Quarterly report2026-05-07

    Q1 2026: opex steps up as Voyage/Panorama/Emerge enroll; cash sufficient into key readouts.

  8. DEF 14A Proxy statement2026-04-27

    Proxy filed for 2026 annual meeting — routine director/comp/auditor votes.

  9. 10-K Annual report2026-02-26

    FY25: net loss widened to -$184M, R&D +80% on Phase 3 ramp; cash $258M, debt up.

Recent filings

all on EDGAR ↗
4Period ending 2026-06-252026-06-26open ↗4Period ending 2026-06-252026-06-26open ↗4Period ending 2026-06-252026-06-26open ↗4Period ending 2026-06-252026-06-26open ↗4Period ending 2026-06-252026-06-26open ↗144Filing2026-06-25open ↗144Filing2026-06-25open ↗144Filing2026-06-25open ↗144Filing2026-06-25open ↗144Filing2026-06-25open ↗8-KPeriod ending 2026-06-222026-06-24open ↗424B5Filing2026-06-24open ↗

Quality score

F
ValueGrowthProfitHealthMom.
Value—
GrowthF
ProfitabilityF
Financial healthB-
Momentum—
  • ✗Profitable (positive net income)
  • ✗Return on equity above 15%
  • ✓Liabilities below 2× equity
Revenue
—
Net margin
—
ROE
-55.3%
P/E
—

SEC fundamentals · FY 2025

■ revenue · ■ net income, by fiscal year

Net income-$184M-69.1%
Operating income-$166M-60.0%
Diluted EPS-$2.06-33.8%
Cash & equivalents$258M-5.8%
Total assets$440M+45.7%
Total liabilities$108M+77.5%
Stockholders' equity$332M+37.6%
L/E: 0.32x

Frequently asked

Is Definium Therapeutics, Inc. (DFTX) a buy?
DFTX currently carries a Avoid rating with 4/5 conviction, derived from its latest SEC filings. Pre-revenue psychedelic biotech burning $132M/yr with binary Phase 3 readouts in mid-to-late 2026 — coin-flip, not an investment.
What is Definium Therapeutics, Inc.'s quality score?
DFTX scores 35.46153846153846/100 (grade F) on a SEC-grounded quality model spanning value, growth, profitability, financial health and momentum.

Sources: SEC EDGAR (CIK 0001813814, latest 10-Q filed 2026-05-07) · EODHD · analysis by claude-code · as of 6/25/2026, 12:46:16 PM.

Research and education only — not financial advice. EDGAR is not a registered investment adviser or broker-dealer and gives no personalized advice. Every call is impersonal — identical for all users, generated on a schedule from SEC filings plus a delayed/third-party price feed — may be wrong or out of date, and is not a recommendation to buy or sell any security. The operator and an affiliated trading operation may hold or trade the securities EDGAR rates; see Disclosures. Past performance does not guarantee future results. Do your own research.

Insider activity

Form 4 · SEC

Last 90 days: 0 open-market buys · 5 sales

2026-06-25
Sullivan Mark
Chief Legal Officer
Sell13.0K @ $45.03$586K
2026-06-25
Roberts Brandi
Chief Financial Officer
Sell3.01K @ $45.03$136K
2026-06-25
Barrow Robert
Chief Executive Officer
Sell29.2K @ $45.03$1.32M
2026-06-25
Karlin Daniel
Chief Medical Officer
Sell10.0K @ $45.03$452K
2026-06-25
Wiley Matthew T.
Chief Commercial Officer
Sell2.87K @ $45.03$129K
2026-06-22
Wiley Matthew T.
Chief Commercial Officer
Award62.5K
2026-06-22
Barrow Robert
Chief Executive Officer
Award375K
2026-06-22
Roberts Brandi
Chief Financial Officer
Award62.5K

Earnings history

beat/miss · move
2026-05-07Miss -41.4% est▼ -0.94%8-K ↗
2026-02-26Miss -0.5% est▼ -1.87%8-K ↗
2026-01-12Miss -0.5% est▲ +0.29%8-K ↗
2025-11-06Miss -52.6% est▼ -1.65%8-K ↗
2025-10-29Miss -52.6% est▲ +0.31%8-K ↗
2025-07-31Miss -34.5% est▲ +0.66%8-K ↗

Dates from 8-K (Item 2.02); beat/miss = reported EPS vs consensus (Finnhub, recent quarters); move = prior close → close on/after.

Recent news

market news →
Weekly Buzz: IONS, MRK Get FDA Approvals; ACHV Gets CRL; ADCT Cuts Jobs; TECH AcquiredBullish
nasdaq.com· 2026-06-26
Definium Prices $700 Mln Upsized Offering At $34 Per Share To Advance DT120 ODTBearish
nasdaq.com· 2026-06-24
Definium Therapeutics prices $700M upsized public offering at $34.00 a shareBullish
seekingalpha.com· 2026-06-24
Definium Stock Soars 50% as Phase III Depression Study Meets Key GoalsBullish
finance.yahoo.com· 2026-06-23
Definium Therapeutics (DFTX) Hits New High on Impressive Drug Candidate TrialBullish
finance.yahoo.com· 2026-06-23
Stocks Mostly Lower on Weakness in Megacap Tech and Software StocksBullish
nasdaq.com· 2026-06-22

Vs tracked universe

compare →

1043 tracked peers · median

EDGAR Score35 vs 67
Revenue growth— vs 7.1%
Net margin— vs 10.5%
Return on equity-55.3% vs 12.4%
P/E— vs 25.5

News sentiment

EODHD · 7d
Bearish
-0.36
vs typical · 17 articles
↑ improving

Recent news tone vs the market's typical (which skews positive). A soft signal, not a recommendation.