Pulling SEC filings + quote and writing the call…

Mirum Pharmaceuticals, Inc.
Next earnings Aug 4, 2026 (after close) · consensus $-0.70 EPS, $168M rev
Last earnings +4.0% on 2026-05-06
Rare-disease pharma scaling fast — revenue +54.7% to $521M, near breakeven, cash-flow positive — growth nearing the profitability inflection.
Revenue $521M · FY2025
Mirum Pharmaceuticals is a commercial-stage rare-disease company whose revenue ramp is the standout here — and unlike a typical pre-revenue biotech, it has approved, selling products. FY2025 revenue grew 54.7% to $521M, the latest leg of a remarkable trajectory from just $19.1M in FY2021 (through $77.1M, $186M and $337M). Crucially, the company is approaching profitability: net loss narrowed dramatically to -$23.4M from -$87.9M, operating loss shrank to -$22.1M, and operating cash flow swung firmly positive to $55.8M (+440.7%). That is the signature of a specialty-pharma model reaching scale, where commercial revenue is starting to cover the fixed cost base.
| Line item | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|
| Revenue | $19.1M | $77.1M | $186M | $337M | $521M |
| Gross profit | — | — | — | — | — |
| Operating income | -$173M | -$131M | -$109M | -$87.6M | -$22.1M |
| Net income | -$84.0M | -$136M | -$163M | -$87.9M | -$23.4M |
| Diluted EPS | -$2.77 | -$4.02 | -$4.00 | -$1.85 | -$0.47 |
| Net margin | -438.9% | -176.0% | -87.7% | -26.1% | -4.5% |
Annual figures from SEC 10-K XBRL filings. Open the filing links below for full statement detail.
Computed from SEC XBRL annual figures + the current quote. EV and ROIC use long-term + current debt where filed; estimates, not investment advice.
Sources: SEC EDGAR (CIK 0001759425, latest 10-Q filed 2026-05-06) · EODHD · analysis by claude-code · as of 6/21/2026, 8:56:37 PM.
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Last 90 days: 0 open-market buys · 1 sale
| 2026-06-17 | Howe Jolanda SVP, GLOBAL CONTROLLER | Sell | 2.59K @ $101.95 | $264K |
Dates from 8-K (Item 2.02); beat/miss = reported EPS vs consensus (Finnhub, recent quarters); move = prior close → close on/after.
1042 tracked peers · median
Recent news tone vs the market's typical (which skews positive). A soft signal, not a recommendation.