Pulling SEC filings + quote and writing the call…

Olema Pharmaceuticals, Inc.
Next earnings Aug 10, 2026 · consensus $-0.56 EPS
Last earnings -6.0% on 2026-05-12
Pre-revenue biotech burning $147M/yr with only $48M cash — binary OPERA-01 readout in fall 2026 on a depleted balance sheet.
Olema is a clinical-stage biopharma with zero product revenue and a widening loss profile: net loss expanded to -$162M in FY2025 from -$129M in FY2024 (-25.5% YoY), driven by R&D ramp to $158M (+26.6%) as OPERA-01 and OPERA-02 advance. Management explicitly states they 'expect to incur significant and increasing losses for the foreseeable future,' and the entire equity story rests on palazestrant — a CERAN/SERD for ER+/HER2- metastatic breast cancer — with top-line Phase 3 OPERA-01 data due fall 2026 and a potential NDA in 2027. This is a binary, single-asset bet.
| Line item | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|
| Revenue | — | — | — | — | — |
| Gross profit | — | — | — | — | — |
| Operating income | -$71.5M | -$107M | -$105M | -$142M | -$179M |
| Net income | -$71.1M | -$105M | -$96.7M | -$129M | -$162M |
| Diluted EPS | -$1.80 | -$2.62 | -$2.14 | -$2.20 | -$1.87 |
| Net margin | — | — | — | — | — |
Annual figures from SEC 10-K XBRL filings. Open the filing links below for full statement detail.
Computed from SEC XBRL annual figures + the current quote. EV and ROIC use long-term + current debt where filed; estimates, not investment advice.
Annual meeting vote results; routine director/auditor ratification disclosure.
Reg FD investor/conference materials posted; no new financial commitments.
Reg FD update — likely conference presentation on palazestrant program.
Q1'26: continued operating losses, R&D-heavy spend pressures $48M cash base.
Q1'26: continued operating losses, R&D-heavy spend pressures $48M cash base.
Entered new material agreement creating direct financial obligation (debt/financing).
2026 proxy: routine board, comp and auditor ratification items.
2026 proxy: routine board, comp and auditor ratification items.
FY25 net loss $162M; cash fell 65% to $48M — funding need before OPERA-01 readout.
Sources: SEC EDGAR (CIK 0001750284, latest 10-Q filed 2026-05-12) · EODHD · analysis by claude-code · as of 6/25/2026, 2:38:22 PM.
Research and education only — not financial advice. EDGAR is not a registered investment adviser or broker-dealer and gives no personalized advice. Every call is impersonal — identical for all users, generated on a schedule from SEC filings plus a delayed/third-party price feed — may be wrong or out of date, and is not a recommendation to buy or sell any security. The operator and an affiliated trading operation may hold or trade the securities EDGAR rates; see Disclosures. Past performance does not guarantee future results. Do your own research.
Dates from 8-K (Item 2.02); beat/miss = reported EPS vs consensus (Finnhub, recent quarters); move = prior close → close on/after.
1044 tracked peers · median
Recent news tone vs the market's typical (which skews positive). A soft signal, not a recommendation.