Pulling SEC filings + quote and writing the call…

BeOne Medicines Ltd.
Next earnings Aug 28, 2026
Last earnings +5.3% on 2026-05-06
Best-in-class oncology franchise just turned GAAP-profitable, but a 73x sales and 1,400x earnings price leaves no margin of safety.
Revenue $5.34B · FY2025
Middling fundamentals and a rich price (~97% above fair value) leave little margin of safety — a wait-and-see.
BeOne (ONC) has reached a genuine inflection point. FY2025 revenue hit $5.34B, up 40.2% YoY, and the company crossed into GAAP profitability for the first time, swinging from a -$645M net loss in FY2024 to +$287M net income (+144.5%). The engine is BRUKINSA, which management calls the global revenue leader in the BTK inhibitor class, contributing $3.9B in 2025 revenue (+48.6%). Operating income rose 178.7% to $447M, gross margin is an excellent 87.5%, and operating cash flow exploded to $1.13B (from roughly $113M the prior year). The balance sheet is sturdy: $4.55B cash (+73.1%), liabilities/equity of just 0.88x, and $6.23B current assets against $1.83B current liabilities. R&D of $2.15B grew only 9.9%, so revenue is now scaling faster than spend — the operating leverage thesis is real.
| Line item | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|
| Revenue | $1.18B | $1.42B | $2.46B | $3.81B | $5.34B |
| Gross profit | $1.01B | $1.13B | $2.08B | $3.22B | $4.67B |
| Operating income | -$1.44B | -$1.79B | -$1.21B | -$568M | $447M |
| Net income | -$1.46B | -$2.00B | -$882M | -$645M | $287M |
| Diluted EPS | -$1.21 | -$1.49 | -$0.65 | -$0.47 | $0.19 |
| Net margin | -123.9% | -141.5% | -35.9% | -16.9% | 5.4% |
Annual figures from SEC 10-K XBRL filings. Open the filing links below for full statement detail.
Computed from SEC XBRL annual figures + the current quote. EV and ROIC use long-term + current debt where filed; estimates, not investment advice.
Sources: SEC EDGAR (CIK 0001651308, latest 10-Q filed 2026-05-06) · EODHD · analysis by claude-code · as of 6/21/2026, 7:04:55 PM.
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Last 90 days: 0 open-market buys · 13 sales
| 2026-06-23 | Wu Xiaobin President and COO | Sell | 1.29K @ $276.26 | $357K |
| 2026-06-23 | OYLER JOHN Chief Executive Officer | Sell | 1.80K @ $273.30 | $492K |
| 2026-06-23 | OYLER JOHN Chief Executive Officer | Sell | 1.29K @ $274.12 | $354K |
| 2026-06-23 | OYLER JOHN Chief Executive Officer | Sell | 320.00 @ $275.10 | $88.0K |
| 2026-06-23 | Wang Lai President, Global Head of R&D | Sell | 1.07K @ $276.74 | $296K |
| 2026-06-16 | Wu Xiaobin President and COO | Sell | 1.36K @ $266.76 | $362K |
| 2026-06-16 | OYLER JOHN Chief Executive Officer | Sell | 1.65K @ $264.87 | $437K |
| 2026-06-16 | OYLER JOHN Chief Executive Officer | Sell | 1.71K @ $265.99 | $455K |
| 2026-06-16 | OYLER JOHN Chief Executive Officer | Sell | 333.00 @ $266.69 | $88.8K |
| 2026-06-16 | Lee Chan Henry SVP, General Counsel | Sell | 590.00 @ $265.98 | $157K |
| 2026-06-16 | Wang Lai President, Global Head of R&D | Sell | 1.17K @ $265.39 | $310K |
| 2026-06-11 | Ball Titus B. Principal Accounting Officer | Award | 31.2K |
Dates from 8-K (Item 2.02); beat/miss = reported EPS vs consensus (Finnhub, recent quarters); move = prior close → close on/after.
1043 tracked peers · median
Recent news tone vs the market's typical (which skews positive). A soft signal, not a recommendation.