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Home›Stocks›PRLD

PRLD

Prelude Therapeutics Inc

Next earnings Aug 12, 2026 · consensus $-0.24 EPS

Last earnings -3.3% on 2026-05-12

Sell
$4.38
▲ +6.83%
$4.38▲ +409.01%
over 1Y
L $0.78EODHDH $5.52
Earnings Dividend Split Congress buy Congress sellGrouped by date · hover a pin to expand
Today+6.8%
1W+1.4%
1M+5.3%
3M+43.6%
YTD+60.4%
1Y+409.0%
OverviewFinancialsValuationQualityTimelineFilings
Rating
Sell
Quality
D
Valuation
Fair value
Filings
Watch
Sell
Conviction
Horizon
Medium (3–12mo)
Street · 9 analysts
Buy

Revenue grew 73.4% YoY; but unprofitable (net margin -819.6%).

Prelude Therapeutics Inc shows $12.1M in FY2025 revenue (+73.4% YoY), a -819.6% net margin, and -145.0% ROE.

Financials · annual, by fiscal year

Line itemFY21FY22FY23FY24FY25
Revenue———$7.00M$12.1M
Gross profit—————
Operating income-$114M-$124M-$132M-$140M-$105M
Net income-$112M-$115M-$122M-$127M-$99.5M
Diluted EPS-$2.43-$2.44-$2.02-$1.68-$1.29
Net margin———-1816.8%-819.6%

Annual figures from SEC 10-K XBRL filings. Open the filing links below for full statement detail.

Key statistics

Valuation

Enterprise value$241M
EV / EBITDA—
EV / Sales19.8
EV / FCF—
P / FCF—
PEG (trailing)—
Earnings yield-36.1%
FCF yield-20.4%

Quality & risk

ROIC (est.)-120.4%
Free cash flow-$56.4M
Total debt—
Net cash$35.3M
Altman Z-Score-6.40 distress
Piotroski F-Score3/7

Capital returns

Buyback yield—
Dividend yield (est.)—
Shareholder yield—
Shares Δ YoY+14.2%

Computed from SEC XBRL annual figures + the current quote. EV and ROIC use long-term + current debt where filed; estimates, not investment advice.

Disclosure timeline

SEC · 8-Ks + reports
Some governance/structural items recently, but no outright red flags.
  1. 8-K Shareholder vote2026-06-10
  2. 8-K Earnings results2026-05-12
  3. 10-Q Quarterly report2026-05-12
  4. DEF 14A Proxy statement2026-04-29
  5. 8-K Material agreement2026-04-21
  6. 8-K Reg FD disclosure2026-04-20
  7. 8-K Officer / director change2026-04-15
  8. 8-K Other event2026-03-12
  9. 10-K Annual report2026-03-10

Recent filings

all on EDGAR ↗
4Period ending 2026-06-092026-06-10open ↗4Period ending 2026-06-092026-06-10open ↗4Period ending 2026-06-092026-06-10open ↗4Period ending 2026-06-092026-06-10open ↗4Period ending 2026-06-092026-06-10open ↗4Period ending 2026-06-092026-06-10open ↗8-KPeriod ending 2026-06-092026-06-10open ↗10-QPeriod ending 2026-03-312026-05-12open ↗8-KPeriod ending 2026-05-122026-05-12open ↗4Period ending 2026-05-012026-05-04open ↗ARSPeriod ending 2025-12-312026-04-29open ↗DEFA14AFiling2026-04-29open ↗

Quality score

D
ValueGrowthProfitHealthMom.
ValueF
GrowthA+
ProfitabilityF
Financial healthC+
Momentum—
  • ✓Revenue growing year-over-year
  • ✗Profitable (positive net income)
  • ✗Net margin above 10%
  • ✗Return on equity above 15%
  • ✓Liabilities below 2× equity
Revenue
$12.1M
+73.4% YoY
Net margin
-819.6%
ROE
-145.0%
P/E
—

SEC fundamentals · FY 2025

'21'22'23'24'25

■ revenue · ■ net income, by fiscal year

Revenue$12.1M+73.4%
Net income-$99.5M+21.8%
Operating income-$105M+25.2%
Diluted EPS-$1.29+23.2%
Cash & equivalents$35.3M+182.6%
Total assets$141M-19.5%
Total liabilities$72.7M+65.0%
Stockholders' equity$68.6M-47.8%
Op.: -861.3%L/E: 1.06x

Frequently asked

Is Prelude Therapeutics Inc (PRLD) a buy?
PRLD currently carries a Sell rating with 2/5 conviction, derived from its latest SEC filings. Revenue grew 73.4% YoY; but unprofitable (net margin -819.6%).
What is Prelude Therapeutics Inc's quality score?
PRLD scores 46.33333333333333/100 (grade D) on a SEC-grounded quality model spanning value, growth, profitability, financial health and momentum.

Sources: SEC EDGAR (CIK 0001678660, latest 10-Q filed 2026-05-12) · EODHD · as of 6/26/2026, 6:55:21 PM.

Research and education only — not financial advice. EDGAR is not a registered investment adviser or broker-dealer and gives no personalized advice. Every call is impersonal — identical for all users, generated on a schedule from SEC filings plus a delayed/third-party price feed — may be wrong or out of date, and is not a recommendation to buy or sell any security. The operator and an affiliated trading operation may hold or trade the securities EDGAR rates; see Disclosures. Past performance does not guarantee future results. Do your own research.

Insider activity

Form 4 · SEC
2026-04-27
RA CAPITAL MANAGEMENT, L.P.
10% owner
Disposed (J)1.41M

Earnings history

beat/miss · move
2026-05-12Beat +48.7% est▼ -3.33%8-K ↗
2026-03-10Miss -575.7% est▲ +16.50%8-K ↗
2025-11-12Beat +30.2% est▲ +8.89%8-K ↗
2025-08-14Beat +8.5% est▲ +4.19%8-K ↗
2025-05-06—▼ -3.12%8-K ↗
2025-03-10—▼ -8.97%8-K ↗

Dates from 8-K (Item 2.02); beat/miss = reported EPS vs consensus (Finnhub, recent quarters); move = prior close → close on/after.

Recent news

market news →
Goldman Sachs Initiates Coverage of Prelude Therapeutics (PRLD)Bullish
finance.yahoo.com· 2026-05-31
Prelude Therapeutics Prices Of $90 Mln Offering Of Shares And Pre-Funded WarrantsBearish
nasdaq.com· 2026-04-21
Myriad Genetics And 2 Other Penny Stocks To Watch CloselyBullish
finance.yahoo.com· 2026-04-06
Prelude Therapeutics Announces Acceptance of Preclinical Abstract for PRT13722, a First-in-Class Oral KAT6A Selective Degrader at the 2026 AACR Annual MeetingBullish
globenewswire.com· 2026-03-17
Prelude Posts Narrower FY25 Loss, Advances JAK2V617F And KAT6 Programs Toward The ClinicBearish
nasdaq.com· 2026-03-11
Prelude Therapeutics GAAP EPS of -$1.29 misses by $0.04, revenue of $12.14MBearish
seekingalpha.com· 2026-03-10

Vs tracked universe

compare →

1044 tracked peers · median

EDGAR Score46 vs 67
Revenue growth73.4% vs 7.1%
Net margin-819.6% vs 10.5%
Return on equity-145.0% vs 12.3%
P/E— vs 25.5