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Research & education only — not financial advice. EDGAR is not a registered investment adviser; calls are impersonal, generated from SEC filings and a delayed/third-party price feed, and may be wrong or out of date. The operator and an affiliated trading operation may hold or trade the securities EDGAR rates — see Disclosures. Do your own research.

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Home›Stocks›PRME

PRME

Prime Medicine, Inc.

Next earnings Aug 5, 2026 · consensus $-0.26 EPS, $1.28M rev

Last earnings -8.7% on 2026-05-07

Sell
$3.43
▲ +7.86%
$3.43▲ +65.70%
over 1Y
L $2.07EODHDH $6.67
Earnings Dividend Split Congress buy Congress sellGrouped by date · hover a pin to expand
Today+7.9%
1W+7.9%
1M+3.9%
3M+1.5%
YTD-2.8%
1Y+65.7%
OverviewFinancialsValuationQualityTimelineFilings
Rating
Sell
Quality
F
Valuation
Fair value
Filings
Watch
Sell
Conviction
Horizon
Medium (3–12mo)
Street · 19 analysts
Buy

Revenue grew 55.3% YoY; but unprofitable (net margin -4342.4%).

Prime Medicine, Inc. shows $4.63M in FY2025 revenue (+55.3% YoY), a -4342.4% net margin, and -166.4% ROE.

Financials · annual, by fiscal year

Line itemFY21FY22FY23FY24FY25
Revenue$0.00$0.00$0.00$2.98M$4.63M
Gross profit—————
Operating income-$84.5M-$117M-$205M-$202M-$208M
Net income-$165M-$122M-$198M-$196M-$201M
Diluted EPS-$14.19-$4.19-$2.18-$1.65-$1.35
Net margin———-6566.6%-4342.4%

Annual figures from SEC 10-K XBRL filings. Open the filing links below for full statement detail.

Key statistics

Valuation

Enterprise value$556M
EV / EBITDA—
EV / Sales120.1
EV / FCF—
P / FCF—
PEG (trailing)—
Earnings yield-32.5%
FCF yield-27.0%

Quality & risk

ROIC (est.)-136.2%
Free cash flow-$167M
Total debt—
Net cash$63.0M
Altman Z-Score-3.44 distress
Piotroski F-Score3/7

Capital returns

Buyback yield—
Dividend yield (est.)—
Shareholder yield—
Shares Δ YoY+37.7%

Computed from SEC XBRL annual figures + the current quote. EV and ROIC use long-term + current debt where filed; estimates, not investment advice.

Disclosure timeline

SEC · 8-Ks + reports
Some governance/structural items recently, but no outright red flags.
  1. 8-K Shareholder vote2026-06-08
  2. 8-K Earnings results2026-05-07
  3. 10-Q Quarterly report2026-05-07
  4. DEF 14A Proxy statement2026-04-23
  5. 8-K Officer / director change2026-04-16
  6. 8-K Earnings results2026-03-03
  7. 10-K Annual report2026-03-03
  8. 8-K Reg FD disclosure2026-01-12
  9. 8-K Earnings results2025-11-07

Recent filings

all on EDGAR ↗
4Period ending 2026-06-052026-06-08open ↗4Period ending 2026-06-052026-06-08open ↗4Period ending 2026-06-052026-06-08open ↗4Period ending 2026-06-052026-06-08open ↗4Period ending 2026-06-052026-06-08open ↗4Period ending 2026-06-052026-06-08open ↗4Period ending 2026-06-052026-06-08open ↗8-KPeriod ending 2026-06-052026-06-08open ↗10-QPeriod ending 2026-03-312026-05-07open ↗8-KPeriod ending 2026-05-072026-05-07open ↗ARSPeriod ending 2025-12-312026-04-23open ↗DEFA14AFiling2026-04-23open ↗

Quality score

F
ValueGrowthProfitHealthMom.
ValueF
GrowthB-
ProfitabilityF
Financial healthC
Momentum—
  • ✓Revenue growing year-over-year
  • ✗Profitable (positive net income)
  • ✗Net margin above 10%
  • ✗Return on equity above 15%
  • ✓Liabilities below 2× equity
Revenue
$4.63M
+55.3% YoY
Net margin
-4342.4%
ROE
-166.4%
P/E
—

SEC fundamentals · FY 2025

'21'22'23'24'25

■ revenue · ■ net income, by fiscal year

Revenue$4.63M+55.3%
Net income-$201M-2.7%
Operating income-$208M-2.9%
Diluted EPS-$1.35+18.2%
Cash & equivalents$63.0M-65.5%
Total assets$343M+15.2%
Total liabilities$222M+53.7%
Stockholders' equity$121M-21.1%
Op.: -4498.1%L/E: 1.84x

Frequently asked

Is Prime Medicine, Inc. (PRME) a buy?
PRME currently carries a Sell rating with 2/5 conviction, derived from its latest SEC filings. Revenue grew 55.3% YoY; but unprofitable (net margin -4342.4%).
What is Prime Medicine, Inc.'s quality score?
PRME scores 39.15686274509803/100 (grade F) on a SEC-grounded quality model spanning value, growth, profitability, financial health and momentum.

Sources: SEC EDGAR (CIK 0001894562, latest 10-Q filed 2026-05-07) · EODHD · as of 6/22/2026, 10:54:16 PM.

Research and education only — not financial advice. EDGAR is not a registered investment adviser or broker-dealer and gives no personalized advice. Every call is impersonal — identical for all users, generated on a schedule from SEC filings plus a delayed/third-party price feed — may be wrong or out of date, and is not a recommendation to buy or sell any security. The operator and an affiliated trading operation may hold or trade the securities EDGAR rates; see Disclosures. Past performance does not guarantee future results. Do your own research.

Earnings history

beat/miss · move
2026-05-07Miss -9.6% est▼ -8.65%8-K ↗
2026-03-03Miss -1.4% est▼ -9.23%8-K ↗
2025-11-07Miss -24.0% est▼ -8.85%8-K ↗
2025-08-07Miss -10.5% est▼ -9.58%8-K ↗
2025-07-30Miss -10.5% est▲ +2.35%8-K ↗
2025-05-08—▼ -7.04%8-K ↗

Dates from 8-K (Item 2.02); beat/miss = reported EPS vs consensus (Finnhub, recent quarters); move = prior close → close on/after.

Recent news

market news →
Ocular Therapeutix vs. Prime Medicine: Which Healthcare Stock Is a Better Buy in 2026?Bullish
finance.yahoo.com· 2026-06-15
Groupe Prime Drink annonce un placement privé et un règlement convenu avec ses créanciersBullish
globenewswire.com· 2026-06-12
Prime Drink Group Announces Private Placement and Agreed Resolution with CreditorsBullish
globenewswire.com· 2026-06-12
Harmony Biosciences Holdings, Inc. (HRMY) Q1 Earnings and Revenues Miss EstimatesBullish
finance.yahoo.com· 2026-05-07
Prime Medicine (PRME) Appoints Svetlana Makhni as Chief Financial OfficerBullish
finance.yahoo.com· 2026-04-23
Groupe Prime Drink annonce une débenture convertible, une nomination au conseil et un octroi d’unités d’actions différéesBullish
globenewswire.com· 2026-04-15

Vs tracked universe

compare →

1044 tracked peers · median

EDGAR Score39 vs 67
Revenue growth55.3% vs 7.1%
Net margin-4342.4% vs 10.5%
Return on equity-166.4% vs 12.3%
P/E— vs 25.5

News sentiment

EODHD · 3d
Bullish
+0.13
vs typical · 4 articles
↑ improving

Recent news tone vs the market's typical (which skews positive). A soft signal, not a recommendation.