Pulling SEC filings + quote and writing the call…

Arcus Biosciences, Inc.
Next earnings Aug 4, 2026 (after close) · consensus $-0.94 EPS, $23.8M rev
Last earnings +0.0% on 2026-05-05
Late-stage oncology biotech with a standout HIF-2 asset (casdatifan) but heavy cash burn, TIGIT failure, and serial dilution — speculative hold.
Revenue $33.0M · FY2025
Arcus is a binary clinical-stage story dressed up as a pipeline play. The economics are unambiguously pre-commercial: FY2025 revenue collapsed to $33M (down 35.3% YoY, almost entirely collaboration milestones from Taiho) against a $523M R&D budget and a $482M operating cash outflow that is nearly triple FY2024's $170M burn. Net loss was $353M, retained deficit has widened to -$1.49B, and net margin of -1,069.7% makes the headline 109.4x P/S meaningless — this stock is valued as an option on the pipeline, not on current financials. ROE of -55.9% and the steadily expanding share count (125M shares, up 18.4% YoY after two 2025 underwritten offerings raising ~$438M gross and a November raise of 15.8M shares at $18.25) confirm that public-market dilution is the operating model.
| Line item | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|
| Revenue | $383M | $38.0M | $37.0M | $51.0M | $33.0M |
| Gross profit | — | — | — | — | — |
| Operating income | $54.0M | -$280M | -$340M | -$330M | -$386M |
| Net income | $53.0M | -$267M | -$307M | -$283M | -$353M |
| Diluted EPS | $0.71 | -$3.71 | -$4.15 | -$3.14 | -$3.29 |
| Net margin | 13.8% | -702.6% | -829.7% | -554.9% | -1069.7% |
Annual figures from SEC 10-K XBRL filings. Open the filing links below for full statement detail.
Computed from SEC XBRL annual figures + the current quote. EV and ROIC use long-term + current debt where filed; estimates, not investment advice.
Annual meeting vote results disclosed; routine governance, no material change
Q1 2026 report; continued heavy R&D spend, casdatifan advancing in Phase 3
Q1 2026 report; continued heavy R&D spend, casdatifan advancing in Phase 3
Annual proxy filed; routine board/comp disclosures, no operational change
Other event disclosed (Item 8.01); likely pipeline/regulatory update
Officer/director change announced under Item 5.02
FY25 10-K: STAR-221 TIGIT failed for futility; casdatifan data strong; $222M cash
FY25 10-K: STAR-221 TIGIT failed for futility; casdatifan data strong; $222M cash
New material agreement & debt obligation; likely Hercules term-loan tranche drawn
Sources: SEC EDGAR (CIK 0001724521, latest 10-Q filed 2026-05-05) · EODHD · analysis by claude-code · as of 6/25/2026, 1:23:21 PM.
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Last 90 days: 0 open-market buys · 4 sales
| 2026-06-24 | Jaen Juan C. President | Sell | 6.43K @ $29.66 | $191K |
| 2026-06-23 | Jaen Juan C. President | Sell | 14.1K @ $27.69 | $389K |
| 2026-06-23 | Jaen Juan C. President | Sell | 1.70K @ $28.06 | $47.6K |
| 2026-06-22 | Jaen Juan C. President | Sell | 9.24K @ $27.03 | $250K |
| 2026-06-11 | Lambert Nicole Director | Award | 5.70K | |
| 2026-06-11 | Machado Patrick Director | Award | 5.70K | |
| 2026-06-11 | KANEKO YASUNORI Director | Award | 5.70K | |
| 2026-06-11 | Tang Carolyn C. General Counsel | Exercise | 34.1K @ $2.57 | $87.7K |
| 2026-06-11 | Lacey David L. Director | Award | 5.70K | |
| 2026-06-11 | FALBERG KATHRYN E Director | Award | 5.70K | |
| 2026-06-11 | Ribas Antoni Director | Award | 5.70K |
Dates from 8-K (Item 2.02); beat/miss = reported EPS vs consensus (Finnhub, recent quarters); move = prior close → close on/after.
1044 tracked peers · median
Recent news tone vs the market's typical (which skews positive). A soft signal, not a recommendation.