SEPN
Septerna, Inc.
Next earnings Aug 10, 2026 · consensus $-0.47 EPS, $16.3M rev
Last earnings +12.9% on 2026-05-11
$37.34
▲ +8.11%$37.34▲ +255.28%
over 1Y
L $10.51EODHDH $37.34
Earnings Dividend Split Congress buy Congress sellGrouped by date · hover a pin to expand
Today+8.1%
1W+8.1%
1M+25.3%
3M+56.4%
YTD+33.5%
1Y+255.3%
Hold
Conviction
Horizon
Medium (3–12mo)
Street · 15 analysts
Buy
Revenue grew 4174.5% YoY; but unprofitable (net margin -106.4%).
Revenue (FY2025) $46.0M · FY2025
Septerna, Inc. shows $46.0M in FY2025 revenue (+4174.5% YoY), a -106.4% net margin, and -12.8% ROE.
Financials · annual, by fiscal year
| Line item | FY23 | FY24 | FY25 |
|---|---|---|---|
| Revenue | $151K | $1.07M | $46.0M |
| Gross profit | — | — | — |
| Operating income | $2.08M | -$80.8M | -$68.3M |
| Net income | $4.18M | -$71.8M | -$48.9M |
| Diluted EPS | $0.29 | -$7.26 | -$1.10 |
| Net margin | 2768.2% | -6678.9% | -106.4% |
Annual figures from SEC 10-K XBRL filings. Open the filing links below for full statement detail.
Key statistics
Valuation
Enterprise value$1.56B
EV / EBITDA—
EV / Sales33.9
EV / FCF14.2
P / FCF15.3
PEG (trailing)—
Earnings yield-2.9%
FCF yield6.5%
Quality & risk
ROIC (est.)-14.1%
Free cash flow$110M
Total debt—
Net cash$121M
Altman Z-Score4.65 safe
Piotroski F-Score4/7
Capital returns
Buyback yield—
Dividend yield (est.)—
Shareholder yield—
Shares Δ YoY+1.0%
Computed from SEC XBRL annual figures + the current quote. EV and ROIC use long-term + current debt where filed; estimates, not investment advice.
Disclosure timeline
SEC · 8-Ks + reportsRoutine disclosure cadence — no material red flags in recent filings.
Recent filings
all on EDGAR ↗144Filing2026-06-26open ↗4Period ending 2026-06-222026-06-24open ↗144Filing2026-06-22open ↗144Filing2026-06-22open ↗4Period ending 2026-06-122026-06-16open ↗144Filing2026-06-12open ↗4Period ending 2026-06-012026-06-03open ↗4Period ending 2026-05-262026-05-28open ↗144Filing2026-05-26open ↗10-QPeriod ending 2026-03-312026-05-11open ↗8-KPeriod ending 2026-05-112026-05-11open ↗ARSPeriod ending 2025-12-312026-04-30open ↗
Frequently asked
- Is Septerna, Inc. (SEPN) a buy?
- SEPN currently carries a Hold rating with 2/5 conviction, derived from its latest SEC filings. Revenue grew 4174.5% YoY; but unprofitable (net margin -106.4%).
- What is Septerna, Inc.'s quality score?
- SEPN scores 48.56862745098039/100 (grade D) on a SEC-grounded quality model spanning value, growth, profitability, financial health and momentum.
Sources: SEC EDGAR (CIK 0001984086, latest 10-Q filed 2026-05-11) · EODHD · as of 6/26/2026, 4:54:51 PM.
Research and education only — not financial advice. EDGAR is not a registered investment adviser or broker-dealer and gives no personalized advice. Every call is impersonal — identical for all users, generated on a schedule from SEC filings plus a delayed/third-party price feed — may be wrong or out of date, and is not a recommendation to buy or sell any security. The operator and an affiliated trading operation may hold or trade the securities EDGAR rates; see Disclosures. Past performance does not guarantee future results. Do your own research.